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Index > Protein center > Inha(Gene name) > Mouse
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  • Inha (Gene name),
  • Inhibin alpha chain (Protein name ),  INHA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Inha;
    Protein name:
    Inhibin alpha chain;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
    Function:
    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Inhibin deficient mice are viable but are acutely sensitive to development of gonadal sex-cord stromal tumors.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    366
    Sequence:
    50:
    MVSQRSLLLL | LLLTLRDVDS | CQGPELVREL | VLAKVKALFL | DALGPPAMDG | 
    100:
    EGGDPGIRRL | PRRHAVGGFM | HRTSEPEEED | VSQAILFPAT | GATCEDQPAA | 
    150:
    RGLAQEAEEG | LFTYVFRPSQ | HIRSHQVTSA | QLWFHTGLGR | KSTAAANSSA | 
    200:
    PLLDLLVLSS | GGPMAVPVSL | GQGPPRWAVL | HLAASAFPLL | THPILVLLLR | 
    250:
    CPLCSCSGRP | ETTPFLVAHT | RARAPSAGER | ARRSTPSVPW | PWSPAALRLL | 
    300:
    QRPPEEPAAH | AFCHRAALNI | SFQELGWDRW | IVHPPSFIFH | YCHGSCGMPT | 
    350:
    SDLPLPVPGV | PPTPVQPLFL | VPGAKPCCAA | LPGSMRSLRV | RTTSDGGYSF | 
    366:
    KYEMVPNLIT | QHCACI
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    String:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Inhibin alpha chain
    Cat.:
    E0395h
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    Packing:
    96T
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    ELISA Kit for Mouse Inhibin alpha chain
    Cat.:
    E0395b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Inhibin alpha chain
    Cat.:
    E0395r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Inhibin alpha chain
    Cat.:
    E0395m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Inhibin alpha chain
    MSDS:
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    ELISA Kit for Mouse Inhibin alpha chain
    Cat.:
    E0395p
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Inhibin alpha chain
    Cat.:
    U0395c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Inhibin alpha chain
    Cat.:
    U0395m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Inhibin alpha chain
    Cat.:
    U0395p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Inhibin alpha chain
    Cat.:
    U0395r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Inhibin alpha chain
    Cat.:
    U0395b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Inhibin alpha chain
    Cat.:
    U0395h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Inhibin alpha chain
    Polyclonal Antibody for Mouse Inhibin alpha chain
    Cat.:
    P0395Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Inhibin alpha chain
    Cat.:
    P0395Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Inhibin alpha chain
    Polyclonal Antibody for Mouse Inhibin alpha chain
    Cat.:
    P0395Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Inhibin alpha chain
    Monoclonal Antibody for Mouse Inhibin alpha chain
    Monoclonal Antibody for Mouse Inhibin alpha chain
    Monoclonal Antibody for Mouse Inhibin alpha chain
    Monoclonal Antibody for Mouse Inhibin alpha chain
    Monoclonal Antibody for Mouse Inhibin alpha chain
    Monoclonal Antibody for Mouse Inhibin alpha chain
    Protein for Mouse Inhibin alpha chain
    Protein for Mouse Inhibin alpha chain
    Protein for Mouse Inhibin alpha chain
    Protein for Mouse Inhibin alpha chain
    Protein for Mouse Inhibin alpha chain
    Protein for Mouse Inhibin alpha chain

    R&D Technical Data

    12% SDS-PAGE analysis

               12% SDS-PAGE analysis

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Activins are expressed in preimplantation mouse embryos and in ES and EC cells and are regulated on their differentiation."
      Albano P.M. , Groome N. , Smith J.C.
      Development117:711-723(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Characterization of mouse inhibin alpha gene and its promoter."
      Su J.G.W. , Hsueh A.J.W.
      Biochem. Biophys. Res. Commun.186:293-300(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N-3.
      tissue: Mammary tumor.
    5. 5.
      "Expression of inhibin alpha-subunit gene during mouse gametogenesis."
      Tone S. , Katoh Y. , Fujimoto H. , Togashi S. , Yanazawa M. , Kato Y. , Higashinakagawa T.
      Differentiation44:62-68(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 49-366
      strain: Swiss Webster.
    6. 6.
      "Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice."
      Matzuk M.M. , Finegold M.J. , Su J.G.W. , Hsueh A.J.W. , Bradley A.
      Nature360:313-319(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice."
      Matzuk M.M. , Finegold M.J. , Mather J.P. , Krummen L. , Lu H. , Bradley A.
      Proc. Natl. Acad. Sci. U.S.A.91:8817-8821(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    8. 8.
      "Transgenic models to study the roles of inhibins and activins in reproduction, oncogenesis, and development."
      Matzuk M.M. , Kumar T.R. , Shou W. , Coerver K.A. , Lau A.L. , Behringer R.R. , Finegold M.J.
      Recent Prog. Horm. Res.51:123-154(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;REVIEW
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